Monofluorophosphate와 Chlorhexidine 및 Flavonoid배합세치제의 치면세균막형성억제효과와 구취감소효과에 관한 실용실험적 연구
A CLINICAL STUDY OF TOOTHPASTE CONTAINING MONOFLUOROPHOSPHATE, CHLORHEXIDINE, FLAVONOID & VITAMINE-E ON THE INHIBITION OF DENTAL PLAQUE FORMATION & REDUCING ORAL MALORDOR
김종배, 김영재, 문현수, 서현석, 진보형,
소속 상세정보
김종배 ( ) - 서울대학교 치과대학 예방치학교실
김영재 ( ) - 서울대학교 치과대학 예방치학교실
문현수 ( ) - 서울대학교 치과대학 예방치학교실
서현석 ( ) - 서울대학교 치과대학 예방치학교실
진보형 ( ) - 서울대학교 치과대학 예방치학교실
KMID : 0355419910150020187
Abstract
In order to evaluate the effects of therapeutic toothpastes containing monofluorophosphate, Vitamine-E, Flavonoid, Chlorhexidine, on the inhibition of dental plaque forma ion, the Authors had examined the oral status of 50 students aged twentieth. Then they ware given
with cosmetic toothpaste and therapeutic toothpaste in due sequence. At the same time, all students were given with straight handled mixed bristled toothbrush and directed to brush teeth with toothpaste and toothbrush offered.
The patient hygiene performance were examined in the 7th day, after that they changed heir toothpaste to another one. So, each of them could use 2 toothpastes for 7 days respectively.
On the other hand, to evaluate the reducing effects of dentifrice containing chlorhexidine +n the numbers of Streptococcus mutans, 11 adults aged twentieth were experimented. They used offered toothbrush and chlorhexidine dentifrice and cosmetic dentifrice for 1 week and 3 reeks. To collect data, every volunteers rinsed their mouth with 0.1% pepton solution, the rinsing solutions were inoculated into MSBagar plate. After 3days anaerobic incubation finder the conditions of 10% H2, 10% Co2, 80% N2, The colony forms were identified by 9 biochemical tests.
While, to evaluate the malodor reducing efficiency, the authors analyzed the volatile sulfur compounds from the breath after ingestion of garlic powder. 10 adults aged twentieth were examined.
To obtained adequate data, expirating breath was collected into sampling loop. after ingestion of garlic powder, the subject cleansed the oral cavity by one of the designated methods and reevaluated at 2, 7,12 and 17minutes after ingestion of garlic powder. Gas chromatographic techic was employed for the evaluation of volatile sulfur compounds in mouth air. The percent change in VSC concentration of air samples were calculated in relation to values of it after ingestion of garlic powder immediately.
Thereafter. the data was compared statistically and discussed
The obtained results were as follows;
1. Therapeutic toothpastes inhibited plaque formation more effectively than cosmetic toothpaste.
2. After the use of therapeutic toothpaste containing MVFC, the numbers of
Streptococcus mutans were decreased both 1 week (P < 0.01) and 3wecks ( < 0.05).
3. Therapeutic toothpaste containing MVFC reduced more methyl mercatan and allyl
mercaptan (P < 0.05) than control cosmetic toothpaste.
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